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Triumeq® Tablets for HIV-1
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Triumeq® is a prescription HIV-1 treatment that combines dolutegravir, abacavir, and lamivudine in one daily tablet. You can place your order with US delivery from Canada through Border Free Health. Many patients compare Triumeq without insurance to manage out-of-pocket spending.
What Triumeq Is and How It Works
This medicine is a complete antiretroviral regimen for appropriate adults and adolescents. It contains an integrase inhibitor (dolutegravir) and two nucleoside reverse transcriptase inhibitors (abacavir, lamivudine). Together, they block HIV replication at different steps, which helps reduce viral load when taken as prescribed. As a fixed-dose option, it removes the need to combine separate pills.
Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
The class combination in Abacavir dolutegravir lamivudine tablets has been widely used under clinician supervision. Before starting, patients should be screened for the HLA‑B*5701 allele due to the risk of abacavir hypersensitivity. Clinicians also assess hepatitis B status because stopping lamivudine can lead to HBV flare in coinfected individuals. Use follows the official label and your prescriber’s guidance.
Learn more about the condition on our HIV page and the broader class on Antivirals. For background on modern regimens, see Biktarvy Hiv Treatment and Tenvir Af Uses.
Who It’s For
This treatment is indicated for adults and adolescents who meet weight-based criteria and do not require dose adjustments for the individual components. The abacavir dolutegravir lamivudine 600-50-300 mg combination is generally chosen for patients without known resistance to its components. It is not recommended in moderate or severe liver impairment, in creatinine clearance below the threshold that requires lamivudine adjustment, or in anyone with the HLA‑B*5701 allele. People with hepatitis B coinfection may need additional HBV-active therapy.
Dosage and Usage
The usual Triumeq dose is one tablet by mouth once daily, with or without food. Swallow the tablet whole; do not crush or split unless a clinician advises otherwise. Separate from aluminum- or magnesium-containing antacids by taking this medicine at least two hours before or six hours after them. Calcium or iron can be taken together with food; otherwise separate similarly. Avoid use with dofetilide. If you are prescribed rifampin, certain seizure medicines, or St. John’s wort, your prescriber may choose a different regimen because the fixed-dose tablet cannot be adjusted to overcome strong inducers. Always follow the FDA-approved label and your prescriber’s instructions.
For more on testing and care, see Types Of Hiv Tests and Aptivus For Hiv.
Strengths and Forms
Most adults take Triumeq 600-50-300 mg tablets, a single film-coated tablet containing abacavir 600 mg, dolutegravir 50 mg, and lamivudine 300 mg. A pediatric dispersible tablet formulation (Triumeq PD) exists for eligible children; dosing is weight-based and uses multiple dispersible tablets. Availability may vary by pharmacy and jurisdiction.
Missed Dose and Timing
If you miss a dose, take it as soon as you remember. If it is close to the time of your next scheduled dose, skip the missed one and take the next dose at the regular time. Do not take two doses at once. If vomiting occurs shortly after taking a dose and you are unsure whether it was absorbed, consult the medication guide or your prescriber for advice.
Storage and Travel Basics
Store tablets in the original child-resistant container at room temperature and keep the bottle tightly closed. Protect from excessive moisture and keep out of reach of children and pets. When you travel, carry your medication in your hand luggage with the original label, plus a copy of your prescription if available. Build extra time for security checks, and keep a simple dosing reminder on your phone to help maintain adherence across time zones. If your itinerary includes long flights, pack a small backup supply in a separate bag.
Benefits
This therapy offers single-tablet convenience, which can simplify daily routines. It can be taken with or without food, supporting consistent use. The integrase inhibitor component provides a potent backbone when used according to clinical guidance. For many people, consolidating pills can help reduce errors and support adherence alongside routine monitoring.
Side Effects and Safety
Common Triumeq side effects may include nausea, diarrhea, headache, fatigue, and trouble sleeping. Not everyone experiences these effects, and many are mild and temporary.
- Gastrointestinal upset: nausea, vomiting, or diarrhea
- Neurologic: headache or dizziness
- General: tiredness or malaise
- Sleep: insomnia or vivid dreams
- Laboratory: mild liver enzyme changes
Serious risks are uncommon but need urgent care. Abacavir hypersensitivity is a medical emergency; symptoms can include fever, rash, stomach pain, shortness of breath, cough, fatigue, or achiness. Stop the medicine and seek help immediately if it is suspected; do not restart. Lactic acidosis and severe hepatomegaly with steatosis have been reported with nucleoside analogs. In people with hepatitis B, stopping lamivudine can cause severe flares of hepatitis; monitoring is needed. Integrase inhibitors can increase weight in some patients. Small increases in serum creatinine can occur with dolutegravir due to reduced tubular secretion without affecting actual kidney filtration; your clinician may monitor this.
Drug Interactions and Cautions
Some medicines can reduce effectiveness or raise risks. Do not use with dofetilide. Strong enzyme inducers like rifampin, carbamazepine, phenobarbital, and phenytoin may lower dolutegravir levels; the fixed-dose tablet cannot be adjusted to compensate, so alternative therapy is often selected. Separate from aluminum- or magnesium-containing antacids and certain supplements as noted above. Metformin levels can rise with dolutegravir; clinicians may adjust metformin. Use caution with sorbitol-containing solutions, which can lower lamivudine exposure. Limit alcohol due to abacavir’s hepatic metabolism. Discuss all prescriptions, OTC products, and herbal supplements, including St. John’s wort.
What to Expect Over Time
With steady daily use and follow-up, many patients see reductions in viral load per clinical testing. Energy levels and overall well-being may improve as the immune system stabilizes, though experiences vary. Your healthcare professional will schedule labs to assess viral suppression, liver health, kidney function markers, and potential side effects. Consistency matters. Using reminders, pairing dosing with a daily habit, and keeping a small travel kit can support adherence. If you experience side effects that affect daily life, contact your prescriber to review options.
Compare With Alternatives
Integrase-based options are common. Doravirine-based therapy can be used in certain cases; see Pifeltro® for a non-nucleoside alternative that is combined with NRTIs. Protease inhibitor–based regimens remain appropriate for select patients; Kaletra® Oral Solution is one example used with a backbone. Your prescriber will individualize therapy using guidelines and your clinical history.
Pricing and Access
Border Free Health lists Canadian pharmacy options with transparent pricing. Many compare cash-pay options to lower overall costs compared to typical U.S. retail. If you are looking for a discount, check our Promotions page for current offers and tips that might complement a manufacturer program. We provide order support and encrypted checkout. Orders Ships from Canada to US with clear tracking. Your prescription is required before dispensing.
Availability and Substitutions
Supply can vary. If the requested product is temporarily unavailable, your prescriber may recommend an alternative with a similar clinical role. Pharmacy teams review substitutions only with prescriber authorization.
Patient Suitability and Cost-Saving Tips
This treatment may be suitable for adults and adolescents who meet weight criteria, are HLA‑B*5701 negative, and have no contraindicated interactions. It is not appropriate for people with previous abacavir hypersensitivity, significant hepatic impairment, or those requiring lamivudine dose reductions that the fixed tablet cannot provide. People who are pregnant or planning pregnancy should discuss potential risks and benefits with their prescriber. For coinfection with hepatitis B, clinicians may add HBV-active therapy.
To manage costs, ask your prescriber about multi-month supplies if appropriate, which can reduce per-fill fees. Set refill reminders a week before running out so your order can be processed and your prescription reverified if needed. If your clinician changes your regimen, update us promptly to avoid delays. You can also review our Canada page to understand sourcing.
Questions to Ask Your Clinician
- Eligibility check: Do I need HLA‑B*5701 testing before starting?
- Safety planning: What symptoms suggest abacavir hypersensitivity?
- Interactions: How should I space antacids, calcium, or iron?
- Comorbidities: What if I have hepatitis B or liver concerns?
- Monitoring: How often will my labs be checked after initiation?
- Pregnancy: Is this regimen appropriate if I am planning pregnancy?
- Adherence: What should I do if side effects make dosing difficult?
Authoritative Sources
Review official information and talk with your prescriber:
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Do I need testing before starting Triumeq?
Your clinician will check your medical history and may order HLA‑B*5701 testing because abacavir can cause a serious hypersensitivity reaction in people who carry that allele. They may also evaluate hepatitis B status, liver function, and potential interactions. This information helps confirm that the regimen is appropriate and guides monitoring after you start therapy. Follow your prescriber’s advice and the medication guide included with the product.
How should I take it with antacids, calcium, or iron?
Dolutegravir binds to cations in aluminum- or magnesium-containing antacids. Take the tablet at least two hours before or six hours after those antacids. Calcium or iron can be taken at the same time if you take your dose with food; otherwise separate similarly. If you use multiple supplements, discuss a simple schedule with your healthcare professional to avoid spacing errors and help maintain adherence.
What if I miss a dose or vomit after dosing?
If you miss a dose, take it when you remember unless it is near the time for the next scheduled dose. Skip the missed dose in that case and resume your usual time the next day. Do not double up. If you vomit soon after taking a dose and are unsure it stayed down, check the medication guide and contact your prescriber for individualized guidance based on your overall treatment plan.
Can I take this medicine during pregnancy?
Use in pregnancy should be individualized. Your prescriber will weigh benefits and risks, including data for integrase inhibitor–based regimens and any potential first-trimester considerations. They will also monitor viral load closely. If you are pregnant or planning to become pregnant, discuss timing, alternatives, and supportive care before making changes. Never stop therapy without speaking to your clinician, as viral rebound can occur.
Does it affect the kidneys?
Dolutegravir can cause small increases in serum creatinine by blocking tubular secretion, which does not reflect an actual drop in kidney filtration. Your clinician may monitor renal markers to distinguish this lab effect from true kidney disease. People with reduced kidney function may need different dosing of lamivudine, which cannot be adjusted within a fixed-dose tablet; your prescriber will choose an appropriate regimen.
Is alcohol safe while taking this medication?
Alcohol can stress the liver and may worsen side effects such as nausea or fatigue. Because abacavir is metabolized by the liver, clinicians often advise limiting alcohol. If you choose to drink, discuss safe limits with your healthcare professional and avoid mixing with other sedating medicines. Report persistent stomach pain, yellowing of the skin, or dark urine promptly, as these can signal liver issues.
Can I switch from another HIV regimen to this one?
Switching should be guided by your treatment history, resistance data, and tolerability. Your prescriber may review past lab results, current side effects, and potential interactions before recommending a change. If you are suppressed without resistance to the components and meet safety criteria, a switch may be considered. Do not stop your current therapy or start a new one without a clear plan and follow-up arranged by your clinician.
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