Xarelto

Uses of Xarelto 

Xarelto (rivaroxaban) is an anticoagulant (blood thinner) utilized to prevent and treat blood clots. It is commonly prescribed for reducing the risk of stroke and systemic embolism in patients dealing with nonvalvular atrial fibrillation, treating deep vein thrombosis (DVT) and pulmonary embolism (PE), and preventing DVT, which can lead to PE, in patients undergoing knee or hip replacement surgery.

Precautions and Warnings

Xarelto raises the risk of bleeding and can cause serious or fatal bleeding. Tell your doctor if you are scheduled for surgery or any invasive procedures, as you may need to stop taking Xarelto temporarily.

Xarelto should be used with caution in patients with severe kidney or liver impairment, as these conditions may affect the drug’s efficacy and safety. It is not recommended during pregnancy unless necessary due to potential risks to the fetus.

Dosage 

The dosage of Xarelto varies based on the condition being treated:

• Nonvalvular Atrial Fibrillation: The typical dose is 20 mg once daily with the evening meal.
• Deep Vein Thrombosis and Pulmonary Embolism: An initial dose of 15 mg twice a day for the first 21 days, then 20 mg once a day.
• Deep Vein Thrombosis Prophylaxis after Knee or Hip Replacement: 10 mg once daily, starting at least 6 to 10 hours after surgery, for 12 days (knee) or 35 days (hip).

Side Effects

Common Side Effects:

• Bleeding
• Bruising
• Gastrointestinal Issues
• Fatigue

More information about Xarelto

• Product Monograph – Health Canada
• U.S. Food and Drug Administration Medication Guide