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Allopurinol Tablets for Gout
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Applies to all products originating from Canada. Maximum allowable quantity equal to a 90-day supply per single order.
Price range: $40.99 through $186.99
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Allopurinol® is a xanthine oxidase inhibitor that lowers uric acid to help prevent flares and kidney stones in gout. This page explains how it works, who it suits, and how to use it safely, with US delivery from Canada even if you are paying without insurance. You will also find label-based guidance and vetted alternatives.
What Allopurinol Is and How It Works
This prescription medicine reduces the body’s production of uric acid by inhibiting xanthine oxidase. Lower uric acid can reduce gout attacks and help protect kidneys from urate deposits. It does not treat sudden gout pain; short-term anti-inflammatory therapy is often used at the start. Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
The treatment is usually taken once daily, often after a meal to support tolerability. Adequate hydration may help limit stone formation. Your clinician will decide on a starting dose and adjust based on uric acid and kidney function.
Who It’s For
This therapy is used for Gout prevention and for chronic management of elevated uric acid. It also supports care in Hyperuricemia from other causes and may be used during cancer care to help prevent uric acid issues related to Tumor Lysis Syndrome, per protocol. Patients with a history of severe skin reactions to this class should avoid use. Those with significant renal impairment, certain genetic risk factors, or liver disease need careful assessment by a clinician.
Some patients ask about allopurinol for gout as a first-line preventive option. Your prescriber may confirm the indication, check labs, and decide if this medicine or another urate-lowering therapy suits your situation and comorbidities.
Dosage and Usage
Follow the official label and your prescriber’s directions. Treatment generally starts low, then is adjusted over time to reach target uric acid. Take the dose after food with a glass of water. Consistent daily use is important. Do not start this medicine during a sudden gout flare; your clinician may begin after the acute episode settles. When initiating therapy, a clinician may recommend short-term prophylaxis with an NSAID or low-dose colchicine to help reduce flare risk during uric acid changes. See label-guided tips and discuss specifics with your healthcare professional.
Helpful habits can support outcomes: take it at the same time each day, drink adequate fluids, and keep lab appointments for uric acid and safety monitoring. If you have kidney issues, your prescriber may use adjusted dosing.
Strengths and Forms
Tablets are widely available in 100 mg and 300 mg strengths. Some markets also have a 200 mg option. Availability can vary by manufacturer and country of origin.
Missed Dose and Timing
If you miss a dose, take it when remembered unless it is close to the next scheduled dose. If it is almost time for the next dose, skip the missed one and return to the regular schedule. Do not double up. If you frequently forget doses, ask about tools like reminders, pill organizers, or synchronized refills.
Storage and Travel Basics
Store tablets at room temperature and keep them dry, away from excess heat and moisture. Keep the medicine in the original container with the label intact and out of reach of children and pets. For travel, carry your prescription label and a copy of the prescription if possible. Pack the medication in your carry-on, and bring extra in case of travel delays. If crossing borders, keep it in original packaging to ease screening and questions.
Benefits
This medicine helps prevent gout flares by lowering uric acid, supporting joint comfort over time. It can reduce urate-related kidney stone risk. Once-daily dosing is convenient for many patients, and dose adjustments can be guided by uric acid measurements. Many people appreciate that this therapy targets the underlying uric acid overproduction, not just flare pain.
Side Effects and Safety
- Common: nausea, diarrhea, abdominal upset
- Headache: usually mild and transient
- Drowsiness: caution with activities requiring alertness
- Rash: report any skin changes promptly
Serious risks are uncommon but require urgent care. Stop the medicine and seek help if you develop a widespread rash, blistering, fever, swollen glands, mouth sores, eye redness, liver issues, or signs of severe hypersensitivity. These can indicate serious reactions such as SJS/TEN or DRESS. Gout flares can occur when starting urate-lowering therapy; clinicians often use flare prophylaxis initially. Always contact a clinician if symptoms worsen or do not improve.
People of certain ancestries may be at higher risk for severe skin reactions when carrying specific HLA variants. Genetic screening may be considered before therapy in higher-risk groups. Discuss screening with your prescriber.
Drug Interactions and Cautions
High-level interactions include azathioprine and mercaptopurine, which may need major dose reductions or alternative plans. Monitor with warfarin. Diuretics and ACE inhibitors can raise certain risks when combined. Ampicillin or amoxicillin may increase rash risk. Theophylline and didanosine can be affected. Alcohol excess can raise uric acid and undermine control. Tell your healthcare professional about all medicines, vitamins, and herbal products you take.
Kidney and liver function influence safety. Dehydration increases stone risk. If you are pregnant, planning pregnancy, or breastfeeding, discuss potential risks and benefits with your clinician before use.
What to Expect Over Time
Uric acid reduction is gradual. Some people experience transient flares early on; this does not mean the medicine is ineffective. Keep taking it as prescribed unless your prescriber tells you to stop. Routine uric acid checks guide dose adjustments. Lifestyle measures like hydration and dietary moderation support the plan. For background on causes of high urate, see What Is Hyperuricemia Cause.
Set reminders, pair dosing with a daily habit, and bring your lab results to appointments. If goals are not met, your clinician may adjust the dose or consider an alternative.
Compare With Alternatives
Another xanthine oxidase inhibitor is Febuxostat, which may be considered when this treatment is not suitable or not tolerated. For flare prevention during initiation, your prescriber may use low-dose Colchicine 0 6mg based on clinical judgment. In hospital settings, aloprim is an IV formulation sometimes used when oral therapy is not feasible; this is specialized care and follows institutional protocols.
Pricing and Access
We offer Canadian pricing with transparent checkout for U.S. patients. You can review the allopurinol price on the product page and see current options based on strength and quantity. This product Ships from Canada to US, and fulfilment occurs after prescription verification. For occasional coupons, visit Promotions. Checkout uses encrypted technology to help protect your information.
For background on an alternative class, you can review Uloric Side Effects Dosing. Country-of-origin details appear under attributes; see Canada for general context.
Availability and Substitutions
If your preferred strength or pack is unavailable, a prescriber may recommend an alternative strength, a different manufacturer, or a class alternative. When appropriate, an allopurinol generic can support continuity of care. If substitution is not suitable, your clinician may consider another urate-lowering therapy based on your history and labs.
Patient Suitability and Cost-Saving Tips
Good candidates can take daily preventive therapy, attend monitoring, and follow guidance on hydration and flare prevention. People with prior severe hypersensitivity to this class or uncontrolled liver or kidney disease may not be suitable. Not for relief of acute gout pain.
- Multi-month fills: can reduce per-fill fees
- Aligned refills: set reminders before travel
- Medication list: avoid interacting drugs
- Hydration plan: support kidney health
- Clinic follow-up: enables timely adjustments
Questions to Ask Your Clinician
- Target uric acid: what goal applies to me?
- Flare prevention: should I take short-term colchicine?
- Monitoring plan: how often for labs and follow-up?
- Kidney function: does my dose need adjustments?
- Rash risk: do I need genetic testing?
- Diet and hydration: what supports my plan?
Authoritative Sources
FDA DailyMed: AllopurinolHealth Canada Product MonographUS Prescribing Information
For gout education and diet planning, explore articles such as Colchicine Side Effects and Colchicine Dosage to understand adjunct care during initiation.
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How long does Allopurinol take to work for gout?
It may take several weeks to see a reduction in gout attacks. It is important to continue the medication regularly to achieve long-term control of uric acid levels.
Can Allopurinol be taken during a gout attack?
No, starting Allopurinol during an active gout attack can worsen symptoms. It is usually started after the attack has resolved.
Do I need to follow a special diet while taking Allopurinol?
Yes, following a low-purine diet and staying hydrated can help improve treatment results and prevent future attacks. Your doctor may give you specific dietary advice.
What should I do if I get a rash while taking Allopurinol?
Stop taking the medication and contact your doctor immediately. A rash could be a sign of a serious allergic reaction that needs urgent care.
Can Allopurinol be used to treat kidney stones?
Yes, Allopurinol may help prevent the formation of certain types of kidney stones caused by high uric acid levels.
Can I start during a gout flare?
This therapy is not intended to treat sudden gout pain. Starting during an acute flare can worsen symptoms. Clinicians usually treat the flare with anti-inflammatory medicines first, then begin urate-lowering therapy when the attack settles. Your healthcare professional will advise on timing and whether short-term prophylaxis, such as low-dose colchicine, is appropriate during initiation to help limit early flares.
How long before uric acid improves?
Uric acid typically declines gradually. Your prescriber may begin with a low dose and adjust over time based on labs and tolerability. Some people experience early flares as urate shifts, which does not mean the therapy is failing. Keep taking it as directed unless told otherwise. Regular monitoring and adherence help your care team decide when adjustments are needed.
What if I develop a rash?
Stop the medicine and seek medical advice promptly if you notice a rash, hives, blistering, mouth sores, fever, or swollen glands. These can be signs of a serious reaction. Do not restart until you have been evaluated. Tell your clinician about any previous severe skin reactions. Some patients may be candidates for genetic testing before use based on ancestry and risk.
Do I need to change my diet?
Dietary moderation can support lower uric acid. Limiting high-purine foods and alcohol, staying hydrated, and maintaining a healthy weight may help. However, medicine is often required for chronic hyperuricemia. Your clinician or a dietitian can provide specific guidance. Do not alter therapy based on diet alone without medical advice.
Can I take it with my other prescriptions?
Some medicines require caution, including azathioprine, mercaptopurine, warfarin, diuretics, ACE inhibitors, certain antibiotics, and theophylline. Always share a complete medication list with your healthcare professional, including over-the-counter products and supplements. Your prescriber will assess interactions and monitoring needs and may adjust therapy if necessary.
Is genetic testing recommended for everyone?
Testing is not universal. Certain ancestries have higher rates of HLA variants linked to severe skin reactions, so screening may be considered before starting in those groups. Your clinician can advise whether testing is appropriate based on your background and medical history. Regardless of testing, report any rash or systemic symptoms promptly.
How is this different from flare treatments?
This medicine lowers uric acid over time to prevent attacks, whereas flare treatments like NSAIDs, steroids, or colchicine address acute pain and inflammation. Many patients use both approaches at different times. Your clinician will determine the best plan for prevention and for managing any breakthrough flare, including whether prophylaxis is needed during initiation.
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