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Brilinta® Tablets for Acute Coronary Syndrome
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Brilinta is an oral antiplatelet for adults who have had a heart attack or acute coronary syndrome. It helps reduce the chance of another clot-related event when used with low-dose aspirin. This page explains key uses, safety basics, and how you can arrange US delivery from Canada, including ways to plan your costs without insurance.
What Brilinta Is and How It Works
Brilinta® contains ticagrelor, a P2Y12 inhibitor that helps prevent platelets from clumping. It works at the ADP receptor on platelets, lowering the risk of clots that can block arteries. The treatment is commonly paired with low-dose aspirin as part of dual antiplatelet therapy after certain heart events or procedures.
Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
This medicine starts working soon after the first dose, with effects maintained by regular dosing. Unlike some alternatives, its action does not require metabolic activation. Because it affects clotting, any new or unusual bleeding should be reported to a clinician.
Some people notice shortness of breath early in therapy. This effect is usually mild and often improves with time. Always check the official label for the most current safety details.
Who It’s For
The treatment is used to reduce the risk of cardiovascular death, heart attack, or stroke in adults with acute coronary syndrome or a history of myocardial infarction. It is also used in people who have stents after percutaneous coronary intervention. Brilinta tablets are taken with aspirin as directed by your prescriber.
People with active bleeding or a history of intracranial hemorrhage should not use this therapy. Those with severe liver disease, a tendency to bleed, or plans for surgery should discuss risks with a clinician. Older adults and those on other blood thinners may need closer monitoring.
For broader context on the condition, see Acute Coronary Syndrome and our overview of related care within Cardiovascular.
Dosage and Usage
Follow your prescriber’s directions and the official label. Many adults start with a one-time loading dose and then take a maintenance dose twice daily. In the first year after an acute coronary syndrome event, Brilinta 90 mg twice daily is commonly used with low-dose aspirin (75–100 mg daily). After the first year, your clinician may continue therapy, often at a lower strength based on the label and your clinical history.
Take doses at the same times each day, with or without food. Do not take more than prescribed. Use only low-dose aspirin as advised, since higher aspirin doses can reduce the treatment’s effectiveness.
If surgery or dental work is planned, tell your care team that you take a P2Y12 inhibitor. Your prescriber will advise how to coordinate timing to manage bleeding risk.
Strengths and Forms
This therapy is available as oral tablets in multiple strengths. Commonly published options include Ticagrelor 90mg tablets for early maintenance use, and another lower strength often used after the first year based on the label. Availability may vary by pharmacy and country of origin.
Tablets are typically film-coated for easy identification. Packaging may differ by manufacturer. Your dispensing pharmacy will provide the patient information leaflet with each fill.
Missed Dose and Timing
If you miss a dose, take the next scheduled dose at its regular time. Do not double up. Staying consistent helps maintain platelet inhibition. Set reminders on your phone or use a pill organizer to support adherence, especially when traveling or recovering from a hospital stay.
Storage and Travel Basics
Store tablets at room temperature in the original container, away from excess heat and moisture. Keep the bottle tightly closed and out of reach of children and pets. Do not store in the bathroom or near a sink where humidity can rise.
When you travel, carry this medicine in your hand luggage. Bring a copy of your prescription and a current medication list. Keep tablets in labeled pharmacy packaging to help with security checks. If you cross time zones, plan your dosing schedule in advance and ask your clinician for guidance.
Prolonged heat exposure can damage medicines. Do not leave tablets in a parked car. If you have questions about safe handling in unusual conditions, consult the official label or your pharmacist.
Benefits
This antiplatelet class helps lower the risk of another heart attack or stroke when added to low-dose aspirin after an acute event. Because it does not require metabolic activation, response is more predictable for many patients compared with some alternatives. Twice-daily dosing allows steady platelet inhibition when taken as directed.
The treatment is part of a broader plan that includes lifestyle changes and other heart medicines. Adherence, regular follow-up, and reviewing your full regimen with a clinician are important for sustained benefit.
Side Effects and Safety
- Bleeding, including easy bruising or nosebleeds
- Shortness of breath or a sensation of air hunger
- Dizziness or headache
- Upset stomach or diarrhea
- Skin rash or itching
Serious risks can include major bleeding, including gastrointestinal or intracranial hemorrhage. Seek urgent care for severe headache, weakness on one side, coughing up blood, or black stools. The treatment may raise uric acid and, rarely, can affect heart rhythm with pauses noted early in therapy. People with severe liver problems, a history of bleeding in the brain, or active bleeding should not use it.
Report any persistent shortness of breath to your clinician. Do not stop the medicine suddenly without medical advice, especially if you have a stent, because stopping early can increase stent thrombosis risk.
For a deeper dive on safety, review our article What Is A Heart Attack and condition background in Acute Coronary Syndrome.
Drug Interactions and Cautions
Strong CYP3A inhibitors (for example, ketoconazole, itraconazole, clarithromycin) and strong CYP3A inducers (such as rifampin, carbamazepine, phenytoin) can change ticagrelor levels. Avoid grapefruit products unless your clinician says otherwise. Combining with other agents that increase bleeding risk, including anticoagulants or chronic NSAID use, can raise bleeding risk.
Tell your clinician about all medicines and supplements you take, including herbals like St. John’s wort. Certain statins (simvastatin, lovastatin) may require attention to dose limits when used together. High-dose aspirin can reduce effectiveness; use the aspirin strength recommended on the label.
What to Expect Over Time
You may not feel a noticeable effect day to day, because this medicine works by preventing clots. Benefits accrue when you take it consistently with low-dose aspirin as directed. Some people experience shortness of breath early, which can improve with time. Discuss any bothersome symptoms so your prescriber can decide whether to continue, adjust, or consider alternatives.
If your care plan continues beyond one year, your clinician may transition to a lower maintenance strength such as Brilinta 60 mg based on the label and your history. Keep all follow-up appointments to review adherence, other heart medicines, and overall risk reduction goals.
Compare With Alternatives
Other approved P2Y12 inhibitors include clopidogrel and prasugrel. Choice depends on clinical scenario, bleeding risk, and prescriber judgment.
- Clopidogrel — Widely used, often once daily
- Prasugrel — Typically for certain PCI patients per label
Your clinician can help decide which agent is appropriate for your situation.
Pricing and Access
We provide transparent options so you can compare brand and the authorized generic when available. Many patients look up the Brilinta price to estimate their budget before ordering. For the generic, people often compare Ticagrelor price with brand to plan out-of-pocket spending.
Because Canadian pricing can be favorable, you can arrange US delivery from Canada after your prescription is verified. Use our site to review current availability, add your prescription details, and proceed through our encrypted checkout. If you’re looking for seasonal deals, visit our Promotions page for current offers.
We cannot quote personal costs here. Your final amount depends on quantity, strength, and dispensing pharmacy. Reach out if you need help submitting prescription documents.
Availability and Substitutions
Supply can vary by strength, pack size, and manufacturer. If a selected strength is unavailable, your prescriber may recommend an alternative strength or agent. Our partner pharmacists coordinate with your clinician as needed before dispensing a substitution.
Patient Suitability and Cost-Saving Tips
This therapy may suit adults after a qualifying heart event when dual antiplatelet therapy is indicated. It is not for people with active bleeding or prior bleeding in the brain. Those with liver impairment, a history of gout, or bradyarrhythmias should review risks and benefits with a clinician.
- Multi-month fills — Fewer refills and better adherence
- Align refills — Reorder before travel or procedures
- Pill organizer — Support consistent twice-daily dosing
- Medication list — Keep an updated list for all visits
- Aspirin plan — Use only low-dose as directed on label
Planning ahead helps reduce missed doses and pharmacy delays. Consider setting calendar reminders for refills and follow-up visits.
Questions to Ask Your Clinician
- Is this the right P2Y12 inhibitor for my heart history?
- How long should I stay on dual antiplatelet therapy?
- What bleeding signs should lead me to seek urgent care?
- Which over-the-counter pain relievers are safer with this therapy?
- Do I need limits on simvastatin or lovastatin while using this?
- How should we plan around upcoming surgery or dental work?
- When might dose or agent changes be considered?
Authoritative Sources
Manufacturer Prescribing Information
Health Canada Drug Product Database
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Can Brilinta be taken with other blood thinners?
Brilinta is usually taken with low-dose aspirin but should not be combined with other blood thinners unless prescribed by a doctor. Taking multiple blood thinners can significantly increase the risk of bleeding.
What should I do if I experience unusual bleeding while on Brilinta?
Contact your doctor immediately if you experience prolonged bleeding, blood in urine or stool, or unexplained bruising. Brilinta increases bleeding risk, but severe bleeding requires medical attention.
Does Brilinta interact with certain foods or drinks?
Brilinta should not be taken with grapefruit or grapefruit juice, as this can affect how the medication works. Alcohol should also be consumed cautiously, as it may increase the risk of bleeding.
How long should I take Brilinta after a heart attack?
Doctors typically prescribe Brilinta for at least 12 months after a heart attack, though some individuals may need to continue treatment longer. Always follow your doctor’s advice regarding treatment duration.
Can Brilinta cause breathing problems?
Some people experience shortness of breath while taking Brilinta. If this occurs, let your doctor know. It is usually mild and temporary, but in some cases, adjustments to the treatment may be needed.
How does ticagrelor differ from clopidogrel?
Both reduce platelet activation but differ in how they work and how quickly they act. Ticagrelor directly and reversibly inhibits the P2Y12 receptor, while clopidogrel is a prodrug that requires metabolic activation. These differences can influence onset, offset, and how clinicians choose between them for certain patients. Your prescriber will consider bleeding risk, stenting details, and clinical history when selecting an option.
Can I take this antiplatelet with aspirin?
Yes, low-dose aspirin is usually taken together unless your clinician advises otherwise. The label recommends low-dose aspirin because higher doses may reduce the medicine’s effectiveness. Do not change your aspirin strength on your own. If you notice unusual bruising, black stools, or prolonged bleeding, contact a healthcare professional promptly.
What should I do before surgery or dental work?
Tell your surgical and dental teams that you take a P2Y12 inhibitor. Your clinician will determine timing around the procedure to balance bleeding risk and stent protection. Never stop therapy on your own. Carry a current medication list and consider a medical alert card indicating you are on an antiplatelet medicine.
Why do some people feel short of breath on therapy?
Shortness of breath can occur early with ticagrelor. It is often mild and may improve with continued use. However, persistent or severe breathlessness needs medical evaluation to rule out other causes and to decide whether to continue. Report symptoms promptly so your prescriber can guide next steps using the official label.
Are there foods or drinks I should avoid?
Avoid grapefruit products unless your clinician says otherwise, because they can affect how the drug is processed. Limit alcohol due to bleeding risk and stomach irritation. Keep a heart-healthy diet that supports your overall treatment plan. Always ask a healthcare professional before starting supplements like fish oil or herbal products.
Can I crush or split the tablets?
Follow label guidance. Some strengths may be swallowed whole, while certain clinical situations allow crushing and mixing with water for administration. Because instructions vary, do not crush or split unless your prescriber specifically directs it. Your pharmacist can provide product-specific advice based on the manufacturer’s leaflet.
What happens if I miss more than one dose?
Do not take extra pills to make up for missed doses. Resume your regular schedule and inform your clinician if you miss multiple doses, especially soon after stent placement. Consistent daily use is important for platelet inhibition. Set alarms or use a weekly pill organizer to help prevent future lapses.
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