Toujeo® Prefilled Pen for Diabetes

This long-acting insulin helps improve blood sugar control in diabetes. It is given once daily using a prefilled pen. This page explains pen options, safe use, and how you can order with US delivery from Canada, including ways to manage costs without insurance.

What Toujeo Is and How It Works

This medicine contains insulin glargine, a basal insulin designed for steady 24-hour coverage. It releases slowly after injection under the skin. The aim is smoother background control between meals and overnight. As part of a complete plan, it works alongside diet, activity, and other therapies your prescriber recommends. See our overview on Long Acting Insulin for context and class basics.

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

This class can be used in adults and certain children with diabetes mellitus when basal insulin is indicated. It is not for treating diabetic ketoacidosis. For background education on insulin types, you can review Types Of Insulin.

Many people transition to a basal insulin when oral medicines are not enough. Some continue rapid-acting insulin at meals. Your healthcare professional will determine whether a single daily dose of a basal product fits your plan.

For broader diabetes resources, explore our Diabetes Care category.

One exact presentation of this class is an insulin glargine U-300 prefilled pen. The higher concentration means a smaller volume for the same units, which can be helpful for larger daily doses.

Who It’s For

This treatment is indicated to improve glycemic control in adults, and in pediatric patients when basal insulin is appropriate per labeling. It may be used in type 1 diabetes with mealtime insulin, or in type 2 diabetes alone or with other antidiabetic agents.

People who should avoid it include anyone with known hypersensitivity to insulin glargine or any component of the product. It is not appropriate for episodes of acute hypoglycemia or for diabetic ketoacidosis. If you have frequent lows, severe kidney or liver disease, or issues with vision or dexterity that affect pen use, discuss safer options and support with your prescriber. See background pages on Type 1 Diabetes and Type 2 Diabetes.

Dosage and Usage

Use this basal insulin once daily at the same time each day, or as directed by your clinician. It is injected subcutaneously into the abdomen, thigh, or upper arm. Rotate injection sites within a region to reduce lipodystrophy risk. Prime the pen per the Instructions for Use before the first dose and when changing needles.

Dosing is individualized. If switching from another basal insulin, follow your prescriber’s conversion plan and monitor closely during the first several weeks. Do not mix this insulin with other products, and do not use it in an insulin pump. Meal-time insulin and other diabetes medicines may still be required for complete control.

Pen sizes vary. Some patients use the Toujeo 3 mL DoubleStar device for higher daily unit needs, while others prefer the smaller pen option. Your pharmacist and prescriber can align pen choice with your dose and technique. For device basics, see Insulin Pen Types.

Strengths and Forms

Toujeo® is supplied as a concentrated basal insulin at 300 units per mL. Pens are prefilled and single-patient use only. Availability can vary by pharmacy and time. Common presentations include:

• Toujeo 1.5 mL SoloStar pen presentation for once-daily dosing.
• Larger-capacity DoubleStar pen designed for patients requiring higher units per injection.

The pen delivers dose in units; you do not need to convert the concentration. Your care team will provide your daily unit target and titration plan based on monitoring and goals.

Missed Dose and Timing

If you miss a dose, take it as soon as you remember on the same day, then return to your usual schedule. Do not take two doses at once. If you miss more than one day, monitor your glucose and contact your prescriber for guidance.

Inject at the same time each day when possible. If your routine changes due to travel or schedule shifts, keep a log to avoid accidental duplication or omission.

Storage and Travel Basics

Unopened pens should be kept in the refrigerator until the expiration date on the carton. In-use pens may be stored at room temperature as directed on the label and kept away from direct heat and sunlight. Do not freeze. Keep out of reach of children and pets. When traveling, carry pens and supplies in your hand luggage with a copy of your prescription. Use a protective case to avoid damage to the pen mechanism.

Discard the pen if it has been exposed to conditions outside the label. Check the solution before use; do not use if it is cloudy, colored, or contains particles. Our pharmacies use temperature-controlled handling when required during transit.

Pen Handling and Sharps Disposal

Read the Instructions for Use for your specific pen before the first dose. Use a new pen needle for each injection. Prime the device as directed to ensure flow. Select the dose in units and inject into lifted skin, holding the needle in place for the recommended seconds to complete delivery.

Never share pens or needles. Place used needles in an FDA-cleared sharps container or a sturdy household alternative if local rules permit. Follow your local guidelines for disposal.

Benefits

This basal insulin provides steady background control with once-daily use. Smaller injection volumes can make higher-dose regimens more practical. The device format supports dose selection in units and has a smooth injection feel for many patients.

The class can reduce fasting glucose and contribute to improved A1C when used as prescribed. It can be combined with mealtime insulin or non-insulin agents to complete a regimen.

Side Effects and Safety

• Low blood sugar symptoms such as shakiness, sweating, or confusion
• Injection site redness or irritation
• Weight gain or swelling
• Allergic reactions including rash or itching

Serious risks include severe hypoglycemia, particularly if food intake is reduced, activity increases, or dosing errors occur. Fluid retention can worsen with thiazolidinediones. Potassium shifts may occur. Do not drive or operate machinery if you feel symptoms of hypoglycemia. Contact a clinician for persistent injection site issues, repeated lows, or signs of systemic allergy.

Drug Interactions and Cautions

Other antidiabetic agents can increase hypoglycemia risk when combined. Beta-blockers may mask some symptoms of low blood sugar. Alcohol can raise or lower glucose unpredictably. Thiazolidinediones may increase fluid retention. Certain antibiotics, ACE inhibitors, and salicylates can affect glucose levels.

Discuss all medicines, vitamins, and supplements with your prescriber. Tell your care team about any planned changes in meal patterns, activity, or travel, as these affect insulin needs. Do not adjust your dose without medical advice.

What to Expect Over Time

After starting or switching basal insulin, your care team may adjust your dose to reach targets safely. Many people see morning readings improve first. A consistent routine with meals, activity, and injections helps the treatment work as intended. Keep checking your glucose as advised and bring logs to appointments. Over time, you and your clinician can decide whether additional medicines or dose changes are needed.

Compare With Alternatives

Other long-acting options include insulin glargine U-100 and fixed-ratio combinations. If you need a U-100 basal alternative, consider Lantus Solostar. For patients who may benefit from basal insulin plus a GLP-1 receptor agonist, discuss whether Soliqua Solostar aligns with your goals. Your prescriber can compare device features and titration methods.

Pricing and Access

You can review current pricing and see typical cash-pay differences compared with local retail. If you plan to order Toujeo pen online, you will upload your valid prescription during checkout. We provide clear information on pen sizes and refill planning so you can align your order with your regimen and reduce pharmacy trips.

Canadian pricing is available with Ships from Canada to US fulfilment. If you are looking for potential offers, check our seasonal Promotions. For broader options by class, see the Diabetes Drugs List resource.

Availability and Substitutions

Supply can vary by size and pack. If a specific pen format is out of stock, your prescriber may suggest a comparable basal insulin or a different pen capacity. Your prescription will guide any substitution. If Toujeo Doublestar/Solostar Prefilled Pen is not available, we will coordinate with your clinician before changes.

Patient Suitability and Cost-Saving Tips

This therapy suits people who need basal insulin and can use a pen device safely. It may be appropriate if fasting glucose is elevated or if oral medicines alone are insufficient. It is not suitable if you have frequent severe lows, lack support for safe injection technique, or need immediate DKA treatment.

• Multi-month fills: consider 60–90 days if your dose is stable
• Align refills: set reminders based on plunger position and units used
• Travel ready: carry backups, needles, and a copy of your prescription
• Technique checks: review injection steps during visits to avoid waste

Talk with your clinician about titration goals, sick-day plans, and what to do if readings trend too low or too high. Small routine adjustments, like consistent injection timing and site rotation, often support steady outcomes.

Questions to Ask Your Clinician

• Is a concentrated basal insulin right for my current A1C goals?
• Which pen size fits my daily unit needs and injection technique?
• How should I monitor and respond to low or high readings?
• What adjustments are typical when switching from another basal?
• Which other medicines should I continue, pause, or watch closely?
• How long should I keep an in-use pen, and when should I discard it?

Authoritative Sources

FDA Prescribing InformationManufacturer Product SiteHealth Canada Drug Product

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Disclaimer: This page is educational and does not replace medical advice. Use medicines only as prescribed by your healthcare professional.