Naltrexone HCL Anhydrous Powder for Compounding

Naltrexone HCL Anhydrous Powder is a USP-grade raw ingredient used by licensed pharmacies to prepare customized medications. It is chosen when prescribers need specific strengths or formulations not readily available as commercial products. You can access Naltrexone HCl anhydrous powder without insurance through our cross-border model with US delivery from Canada.

What Naltrexone Is and How It Works

This ingredient is an opioid receptor antagonist. It binds to mu-opioid receptors and blocks the effects of opioid medicines. In alcohol use disorder, the therapy can help reduce rewarding effects associated with drinking.

Naltrexone HCl bulk powder is intended for extemporaneous compounding under a prescriber’s order. Pharmacists may prepare capsules, solutions, or other dosage forms suitable for the patient’s needs. This work should follow applicable standards and the official label for the active drug.

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

For background information about conditions, you can review resources on Alcohol Use Disorder and Opioid Use Disorder.

Who It’s For

This medicine is prescribed for adults with alcohol use disorder or opioid use disorder as part of a comprehensive treatment plan. It is not for individuals currently using opioids or for those with acute hepatitis or liver failure. A prescriber may request compounded forms when patients need lactose-free, dye-free, or very small doses, or when swallowing tablets is difficult.

People who require ongoing opioid pain therapy should not receive this treatment. An opioid-free period is needed before starting the active drug; the exact duration should be determined by the prescriber. Always inform a healthcare professional about all medicines, supplements, and medical conditions before starting therapy with this ingredient.

Dosage and Usage

Compounded preparations are made according to the prescriber’s directions. The approved oral schedule for the active drug in alcohol use disorder is commonly 50 mg once daily, as reflected in official labeling. For opioid use disorder, treatment is part of a structured program and should begin only after an appropriate opioid-free interval confirmed by the prescriber.

Low Dose Naltrexone powder may be used when a clinician specifically prescribes very small strengths for individual needs. Pharmacists should follow established compounding standards for potency, uniformity, labeling, and stability.

Patient instructions, including when and how to take a compounded capsule or liquid, come from the dispensing pharmacist and the prescriber. If any uncertainty arises, refer to the official label for the active drug and contact the care team.

Strengths and Forms

This pharmaceutical-grade ingredient is supplied as an anhydrous hydrochloride powder for professional compounding. Availability can vary by lot and supplier.

• Naltrexone HCl anhydrous 1 g powder
• 10 g pack size may be offered depending on stock
• USP-grade anhydrous hydrochloride raw ingredient

Please note that specific pack sizes may change. Pharmacies should confirm current options before preparing formulations.

Missed Dose and Timing

Guidance for a missed dose depends on the finished dosage form and the prescriber’s instructions. As a general principle for oral regimens, if a dose is missed and it is not close to the next scheduled time, it may be taken when remembered. If it is near the next scheduled dose, skip the missed one and resume the regular schedule. Do not double doses. Patients should follow pharmacist labeling for the compounded preparation and consult the care team if questions arise.

Storage and Travel Basics

Store the powder in a tightly closed container in a dry place away from moisture. Protect from excessive heat and from direct light. Keep all medicines and compounding ingredients out of reach of children and pets. For travel, keep your prescription label and any compounding documentation. If flying, place medications in original containers in your carry-on for easier screening.

Finished compounded products may have different storage needs than the raw ingredient; follow the label from the dispensing pharmacy. Shipments use standard practices; temperature-controlled handling when required is arranged according to product needs.

Benefits

As an opioid receptor antagonist, the treatment can help reduce the reinforcing effects of alcohol use. In opioid use disorder, it blocks the effects of opioids, helping support abstinence when combined with counseling and monitoring. Compounded preparations allow clinicians to tailor dosage forms and strengths to patient-specific needs, which can support adherence when standard products are unsuitable.

Side Effects and Safety

• Nausea or stomach discomfort
• Headache
• Dizziness or fatigue
• Sleep changes
• Joint or muscle aches

Serious risks can include liver injury, allergic reactions, and the danger of opioid overdose if someone attempts to override the blockade with high opioid doses. People who stop therapy may be more sensitive to opioids than before; overdose can occur with previously tolerated amounts. Seek urgent care for signs like severe abdominal pain, dark urine, yellowing of the skin or eyes, swelling, trouble breathing, or fainting. Review the official label for the active drug and discuss questions with a healthcare professional.

Drug Interactions and Cautions

Do not use this therapy with opioids or opioid-containing cough, pain, or antidiarrheal medicines. Avoid concurrent use with methadone or buprenorphine unless directed by a specialist within a transition plan. Use caution in hepatic impairment, and discuss all medicines and supplements with the prescriber. Tell emergency clinicians about therapy with this antagonist if urgent care is needed; medical staff may need different pain-management strategies.

What to Expect Over Time

When used as directed as part of a comprehensive plan, the active antagonist can support goals like maintaining abstinence from opioids or reducing alcohol’s rewarding effects. Benefits depend on adherence, appropriate counseling, and close follow-up. Some people notice changes in cravings or response to opioids; others require adjustments in the overall treatment plan. Prescribers will reassess response and tolerability at follow-up visits and may change the plan if needed.

Compare With Alternatives

For opioid use disorder, prescribers may choose a partial opioid agonist like Suboxone as part of a supervised plan. For weight management under a different indication, a combination therapy that includes the same antagonist component is available as Contrave Er. The right choice depends on diagnosis, goals, and safety profile. Discuss options with a clinician to match therapy to individual needs.

Pricing and Access

Canadian pricing often provides value compared with typical cash-pay rates. Availability is shown on the product page, and live updates reflect current stock and compounding suitability. Ships from Canada to US with pharmacist verification of the prescription before dispensing.

To check current pricing, visit the product page and review the listed options. For savings, consider multi-month fills when appropriate and ask the prescriber about consolidated refills to reduce per-fill handling costs.

Availability and Substitutions

Supply may vary. If the requested pack size is unavailable, a prescriber may recommend an alternative form or a different configuration that meets the same clinical intent. Pharmacists can also discuss excipient choices to address allergies or sensitivities when making a substitute compounded preparation.

Patient Suitability and Cost-Saving Tips

This therapy may suit adults with alcohol use disorder or opioid use disorder who can avoid opioid use and participate in follow-up care. It is not appropriate for people requiring ongoing opioid analgesics or with certain liver conditions. To reduce overall costs, ask your prescriber about longer-duration prescriptions when clinically suitable and set reminders so refills are requested before supplies run low. Combining refills into fewer fulfilments can also help reduce repeat handling fees.

For more learning, see related content on Mental Health and Weight Management, plus practical insights from Repurposing Semaglutide and our general Side Effects guide. Pharmacists interested in raw materials can also review Minoxidil Powder Micronized as another compounding powder.

Questions to Ask Your Clinician

• Is this antagonist appropriate for my diagnosis and goals?
• How long should I be opioid-free before starting?
• What finished dosage form and strength are best for me?
• Which side effects should I watch for, and when should I call?
• How will this therapy fit with counseling or other supports?
• What monitoring or lab tests will be needed over time?

Authoritative Sources

Ready to proceed? Start your order today for prompt, express shipping with US shipping from Canada. This page is informational and does not replace advice from your healthcare professional.