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Why Is Combigan So Expensive

Post written by BFH Staff Writer on July 24, 2023
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Why Is Combigan So Expensive? Combigan, a widely prescribed brand of medication for glaucoma treatment, has garnered attention for its effectiveness and relatively high cost. Patients and healthcare professionals alike have questioned the reasons behind its expensive price tag. In this article, we delve into the factors contributing to the expense of Combigan and shed light on why this medication remains a costly option for patients.


The Price of Combigan

Many people from The United States of America turn to to order their Combigan because of the cost. On asking one such patient (name withheld for privacy reasons), he said “I’m struggling to afford my Combigan. The high cost is putting a financial burden on me and my family. I rely on as it helps me save a significant amount.” The average retail price of a 5ml bottle of Combigan hovers around $200 to $250 in the United States, and prices may vary in different regions and pharmacies. At BorderFreeHealth, the product is available at $79.99. The patient says, “It does not matter whether I get the medication from Canada or any other country as long as the product is reliable, and affordable. When you are need, you find ways to get them within your resources.”

What do the doctors say about the high costs of Combigan in the US? “As a healthcare provider, it is difficult to witness patients struggling with high medication costs. It can inhibit their ability to access life-saving treatments and adversely impact their overall health outcomes. While some patients may opt for the generic version of Combigan, Brimonidine Tartrate-Timolol, due to its affordability, others rely on brand-name medications and feel the financial burden of their cost,” stated Dr. Lisa Pereira, Physician.

It is important to note that drug prices are subject to change, influenced by factors such as market demand, manufacturing costs, research and development investments, and the healthcare system in which the medication is distributed. “The cost of developing and manufacturing medications is a complex process that involves significant investments in research, clinical trials, and production. These expenses contribute to the final price of the medication.” Says an ex-employee of Novartis. Combigan is no exception.


Factors Influencing the High Cost

  1. Research and Development Costs. Developing new medications involves substantial investments in research, clinical trials, and obtaining reguPoppinsry approvals. Pharmaceutical companies often invest billions of dollars and years of research to bring a drug to market. The costs incurred during this process significantly contribute to the final price of the medication.
  2. Manufacturing Expenses. Pharmaceutical manufacturing involves a complex and intricate process requiring adherence to stringent quality control measures, facility maintenance, and reguPoppinsry guidelines. These factors contribute to the overall manufacturing expenses, which are passed on to the end consumer.
  3. Patent Protection and Exclusivity. When a pharmaceutical company discovers and develops a new medication, they are granted a patent, giving them exclusive rights to manufacture and sell the drug for a certain period. This exclusivity allows companies to recoup their investment and make a profit. During this period, the drug’s generic versions are unavailable, which can keep the prices high. Once the patent protection expires, generic competitors can enter the market, leading to price reductions.
  4. Limited Market Competition. Combigan is a combination medication containing two active ingredients, brimonidine tartrate and timolol maleate. The limited number of competitors manufacturing a similar combination with the same active ingredients contributes to the need for more competitive pressure on the price. The absence of direct alternatives allows pharmaceutical companies to maintain higher pricing levels. 
  5. Marketing and Advertising: Companies spend substantial amounts on marketing and advertising to promote their medications. These costs are often passed on to consumers, contributing to higher prices.
  6. Insurance Coverage and Negotiations. The role of insurance companies and pharmacy benefit managers (PBMs) should be considered when discussing drug prices. Insurance coverage and the negotiations between pharmaceutical manufacturers and insurers play a crucial role in determining the final price paid by patients. The complex nature of these negotiations, including rebates and discounts, can impact the cost of medications.
  7. Distribution and Supply chain: Medications go through a complex supply chain involving wholesalers, distributors, and pharmacies, each adding their markup to the final price. These markups can significantly impact the cost of the medication for patients.

The high cost of Combigan is the result of a combination of the factors mentioned above.

While the high cost of Combigan may seem burdensome to patients, it’s crucial to understand the factors contributing to its expense. Patients should consult with their healthcare providers and explore potential options that can help manage the financial aspects of their treatment without compromising their health.

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